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US 8,729,014 B2Granted
Specific HCV NS3 protease inhibitors
AssigneesRFS Pharma, LLC, Genoscience
InventorsJerome Courcambeck, Philippe Halfon, Mourad Bouzidi, Steven J. Coats, Richard Anthony Whitaker
Life of this patent
Estimating the term…
Abstract
The present invention is directed to compounds, compositions and methods for treating or preventing viral infections, in particular, HCV in human patients or other animal hosts.
Claims20
A compound of Formula (I):
- or a pharmaceutically acceptable salt, thereof, wherein
- J and J1 can be present or absent, and when present, are independently selected from the group consisting of lower alkyl (C1-C6), aryl, arylalkyl, alkoxy, aryloxy, heterocyclyl, heterocyclyloxy, keto, hydroxy, amino, arylamino, carboxyalkyl, carboxamidoalkyl, halo, cyano, formyl, sulfonyl, and sulfonamido;
- and
- R is alkyl (C1-C10), cycloalkyl (C3-C8), aryl, heteroaryl, or heterocyclyl,
- wherein the compound can be present in the form of individual enantiomers, stereoisomers, rotamers, tautomers, racemates, or mixtures thereof.
2 more elements
A compound having the formula:
Dependencies are inferred from the claim text.