Transcutaneous delivery of therapeutic agents
AssigneeAlba Therapeutics Corporation
InventorsDorothea Sesardic, Blake Paterson
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Abstract
The present invention provides materials and methods to facilitate the transcutaneous delivery of therapeutic agents. In some embodiments, agonists of tight junctions are used in compositions to facilitate the uptake of therapeutic agents from the skin. In a particular embodiment, the present invention provides immunogenic compositions comprising a tight junction agonist and an antigen. In a particular embodiment, the present invention provides vaccine compositions comprising a tight junction agonist and an antigen.
Claims11
A transcutaneous dosage composition comprising a therapeutic agent and a transcutaneous absorption enhancing amount of a tight junction agonist, wherein the tight junction agonist comprises the amino acid sequence of SEQ ID NO:
- 198.
Dependencies are inferred from the claim text.