Back to results
US 8,712,500 B2Granted
Image-monitoring method for electroporation treatment and as associated image-monitoring appliance
AssigneeSiemens Aktiengesellschaft
InventorsSebastian Schmidt, Anke Weissenborn
Life of this patent
Estimating the term…
Abstract
An image-monitoring method for an electroporation treatment with an electroporation appliance is provided. The electroporation appliance comprises at least two treatment electrodes and an image-monitoring appliance. At least one image monitoring measurement is performed by the image-monitoring appliance after the administration of a contrast agent and after the electroporation treatment.
Claims17
An image-monitoring method for an electroporation treatment, comprising:
- administrating a contrast agent into a patient;
- performing the electroporation treatment by an electroporation appliance comprising a plurality of treatment electrodes after administrating the contrast agent;
- performing a reference measurement by an image recording appliance immediately after the electroporation treatment;
- performing a continuous image monitoring measurement by the image recording appliance over a time interval after the electroporation treatment;
- determining a relative intracellular contrast agent concentration in comparison to an extracellular contrast agent concentration from the image monitoring measurement;
- determining an absolute intracellular contrast agent concentration from the image monitoring measurement;
- generating an output image showing a course of contrast agent concentration over the time interval by subtracting data in the reference measurement from data in the image monitoring measurement so that a contrast agent difference between an intracellular and an extracellular space in an area affected by the electroporation treatment is intensified;
- and
- displaying the relative and the absolute intracellular contrast agent concentration and the output image on a screen display.
6 more elements
An image-monitoring appliance for an electroporation treatment, comprising:
- a contrast agent unit for administrating a contrast agent into a patient;
- an electroporation appliance comprising a plurality of treatment electrodes for performing the electroporation treatment;
- an image recording appliance for performing:
- a reference measurement immediately after the electroporation treatment, and
- a continuous image monitoring measurement over a time interval after administrating the contrast agent and after the electroporation treatment;
- and
- a control unit for:
- determining a relative intracellular contrast agent concentration in comparison to an extracellular contrast agent concentration from the image monitoring measurement;
- determining an absolute intracellular contrast agent concentration from the image monitoring measurement
- generating an output image showing a course of contrast agent concentration over the time interval by subtracting data in the reference measurement from data in the image monitoring measurement so that a contrast agent difference between an intracellular and an extracellular space in an area affected by the electroporation treatment is intensified;
- and
- a screen display for displaying the relative and the absolute intracellular contrast agent concentration and the output image.
9 more elements
Dependencies are inferred from the claim text.