US 8,712,140 B2Granted

Method of analyzing cell structures and their components

AssigneeIntelligent Virus Imaging Inc.

InventorsMohammed Homman, Ida-Maria Sintorn

Life of this patent

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Abstract

A cell is provided that contains a plurality of virus particles. A first image of a first virus particle and a second image of a second virus particle are taken by electron microscopy technology. The first virus particle is characterized as being in a first maturity stage and the second virus particle as being in a second maturity stage. The first image and the second image are transformed to first and second gray scale profiles, respectively, based on pixel data. The first and second gray scale profiles are then saved as first and second templates, respectively. A third virus particle in a third image is identified. The third image is transformed into a third gray scale profile. The third gray scale is compared to the first and second template to determine a maturity stage of the third virus particle.

Claims11

Dependent claims

A method of analyzing infectious agents, comprising:

providing a sample containing a plurality of an infectious agent;
taking a first image of a first infectious agent and a second image of a second infectious agent;
characterizing the first infectious agent as having a first structure and the second infectious agent as having a second structure;
transforming the first image to a first color scale profile representing a radial density profile of the first infectious agent going from a center of the first infectious agent radially outwardly towards a periphery of the infectious agent or going from the periphery of the first infectious agent radially inwardly towards the center of the first infectious agent;
transforming the second image to a second color scale profile;
saving the first color scale profile as a first template;
saving the second color scale profile as a second template;
identifying a third infectious agent in a third image;
transforming the third image into a third color scale profile;
and
comparing the third color scale profile to the first and second template to determine a structure of the third infectious agent.

8 more elements

Dependencies are inferred from the claim text.

Facts

Application: 13/490,484Filed 7 Jun 2012 · continuation in part
Priority: 15 Apr 2005
Published: US 2012/0243768 A127 Sep 2012
Granted: 29 Apr 2014
Term ends: Not estimatedThe source records don’t support an estimate.

Classification2 codes

G06V 20/698
Microscopic objects, e.g. biological cells or cellular parts: matching; Classification
G06V
Image and video recognition

Family

Application60/594,526Us provisional application · filed 15 Apr 2005
PCT/US2006/005571Parent of this continuation-in-part · filed 17 Feb 2006
US 2012/0243768 A1Pre-grant publication · published 27 Sep 2012
Application11/911,274Parent of this continuation-in-part
US 8,218,834 B2Parent of this continuation-in-part
US 2008/0205740 A1Published application
US 8,712,140 B2This patent

From the US filing history. Foreign family members aren’t listed.