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US 8,710,230 B2Granted
Inhibitors of human immunodeficiency virus replication
AssigneeGilead Sciences, Inc.
InventorsYoula S. Tsantrizos, Murray D. Bailey, Francois Bilodeau, Rene Coulombe, Teddy Halmos, Stephen Kawai, Serge R. Landry, Steven LaPlante, Sebastien Morin, Marc-Andre Poupart, Bruno Simoneau, Lee Fader, Rebekah J. Carson, Mathieu Parisien
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Abstract
Compounds of formula I: wherein R4, R6 and R7 are defined herein, are useful as inhibitors of HIV replication.
Claims1
An isomer, racemate, enantiomer or diasteriomer of compounds of formula (I):
- wherein:
- R4 is aryl optionally substituted with 1 to 3 substituents each independently selected from halo, (C1-6)alkyl, (C2-6)alkenyl, (C1-6)haloalkyl, (C3-7)cycloalkyl, —OH, —O(C1-6)alkyl, —SH, —S(C1-6)alkyl, —NH2, —NH(C1-6)alkyl and —N((C1-6)alkyl)2;
- wherein the (C1-6)alkyl is optionally substituted with hydroxy, cyano or oxo;
- and
- R6 and R7 are each independently selected from H, halo, (C1-6)alkyl and (C1-6)haloalkyl;
- or a salt or an ester thereof.
3 more elements
Dependencies are inferred from the claim text.