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US 8,710,222 B2Granted
2,4-disubstituted pyrimidines useful as kinase inhibitors
AssigneeCelgene Avilomics Research, Inc.
InventorsJuswinder Singh, Russell Petter, Richland Wayne Tester, Arthur F. Kluge, Hormoz Mazdiyasni, William Frederick Westlin, III, Deqiang Niu, Lixin Qiao
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Abstract
The present invention provides 2,4-disubstituted pyrimidine compounds useful as kinase inhibitors, pharmaceutically acceptable compositions thereof, and methods of using the same.
Claims3
A method for inhibiting activity of Bruton's Tyrosine Kinase (BTK), or a mutant thereof, in a patient or in a biological sample comprising the step of administering to said patient or contacting said biological sample with a compound selected from the group consisting of:
- or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.