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US 8,710,219 B2Granted
Phosphoinositide 3-kinase inhibitor with a zinc binding moiety
AssigneeCuris, Inc.
InventorsXiong Cai, Haixiao Zhai, Chengjung Lai, Changgeng Qian, Rudi Bao
Life of this patent
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Abstract
The invention provides a compound of Formula I, Pharmaceutical compositions comprising such compounds and the use of such compounds in the treatment of phosphoinositide 3-kinase related diseases and disorders such as cancer. The instant application further relates to the treatment of histone deacetylase related disorders and diseases related to both histone deacetylase and phosphoinositide 3-kinase.
Claims8
A compound of Formula I:
- or a pharmaceutically acceptable salt thereof, wherein R is hydrogen or an acyl group.
Dependencies are inferred from the claim text.