Compounds, compositions and methods for reducing lipid levels

A compound of Formula V,

• stereoisomers thereof, tautomers thereof, solvates thereof, and pharmaceutically acceptable salts thereof;
• wherein
• R1 and R2 are independently —H, —(CH2)0-6COOR′, —C(O)R″, —OR′, —NR10R11, —C(O)NR10R11, or a substituted or unsubstituted alkyl, alkenyl, cycloalkyl, cycloalkylalkyl, aryl, aralkyl, heteroaryl, heteroarylalkyl, heterocyclyl, or heterocyclylalkyl group;
• or R1 and R2 together are a 1,2-dioxyethylene group;
• provided that R1 and R2 are not both —OR′;
• R3 and R8 are independently —H, —OH, —Cl, —Br, —F, —I, —CN, —NH2, —C(O)NH2, —COOH, or a substituted or unsubstituted alkyl, alkenyl, alkoxy or aralkyl group;
• R3′ is —H, or R3 and R3′ together are an oxo group;
• R4 is —OSO2R″;
• R5 and R6 are independently —H, halogen, —OH, or a substituted or unsubstituted alkoxy group;
• or R4 and R5 together are a methylenedioxy group, or R5 and R6 together are a methylenedioxy group;
• R7 is —H, halogen, —OH, or a substituted or unsubstituted alkyl or alkoxy group;
• R10 and R11 are independently H, —C(O)OR″, or a substituted or unsubstituted alkyl group;
• each R′ is independently a hydrogen, or a substituted or unsubstituted alkyl, alkenyl, cycloalkyl, cycloalkylalkyl, aryl, aralkyl, heteroaryl, heteroarylalkyl, heterocyclyl, or heterocyclylalkyl group;
• and
• each R″ is independently a substituted or unsubstituted alkyl, alkenyl, cycloalkyl, cycloalkylalkyl, aryl, aralkyl, heteroaryl, heteroarylalkyl, heterocyclyl, or heterocyclylalkyl group.