Use of LPA for encouraging pregnancy, and fertility agent
AssigneesJCR Pharmaceuticals Co., Ltd., Masahide Shiotani, Sakae Goto
InventorsMasahide Shiotani, Sakae Goto, Mitsuo Shimizu
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Abstract
The objective is to find compounds which have an activity to improve the success rate of pregnancy and implantation in blastocyst transfer in mammals, to provide a method of producing and using the compounds, and to provide a pregnancy-promoting agent. Disclosed is a pregnancy-promoting agent containing one or more lysophosphatidic acids selected from the group consisting of LPA-C16:0, LPA-C16:1, LPA-C18:0, LPA-C18:1 and LPA-C18:2.
Claims3
A pregnancy-promoting agent for promoting pregnancy of a patient undergoing blastocyst transfer, comprising a mixture of the lysophosphatidic acids
- LPA-C16:0, LPA-C16:1, LPA-C18:0, LPA-C18:1 and LPA-C18:2 and
- wherein the mutual proportion of the content of LPA-C16:0, LPA-C16:1, LPA-C18:0,LPA-C18:1 and LPA-C18:2 is 36-66 :
- 1-2 :
- 5-10 :
- 13-25 :
- 15-28 in molar ratio.
Dependencies are inferred from the claim text.