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US 8,710,030 B2Granted
Phosphonate compounds
AssigneeThe Regents of the University of California
InventorsKarl Y. Hostetler, James R. Beadle
Life of this patent
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Abstract
The present invention relates to phosphonate compounds, compositions containing them, processes for obtaining them, and their use for treating a variety of medical disorders, e.g., osteoporosis and other disorders of bone metabolism, cancer, viral infections, and the like.
Claims19
A compound of the formula:
- wherein
- R1 is hydrogen, —CH3, —CH2OH, —CH2F, —CH═CH2, or —CH2N3;
- B is adenin-9-yl, 2,6-diaminopurin-9-yl, 2-aminopurin-9-yl or a 1-deaza, 3-deaza, or 8-aza analog thereof;
- and
- R8 is alkylglycerol, 1-S-alkylthioglycerol, or alkoxyalkanol.
2 more elements
Dependencies are inferred from the claim text.