Emulsions containing arylboronic acids and medical articles made therefrom
AssigneeSurModics, Inc.
InventorsJoram Slager, Aleksey V. Kurdyumov, Dale G. Swan
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Abstract
The invention provides emulsion compositions that include a hydrophobic compound and an arylboronic acid. An exemplary emulsion comprises a hydrophobic polymer and a halogenated arylboronic acid. Use of an arylboronic acid provides the emulsion with exceptional stability. The stability provides advantages for the formation of articles formed from the emulsion, including microparticles, as well as other implantable or injectable medical articles having polymeric matrices.
Claims25
An emulsion comprising a hydrophobic polymer, an arylboronic acid, a continuous phase, and a discontinuous phase, wherein the hydrophobic polymer is in the discontinuous phase and the arylboronic acid is in the continuous phase.
A method for preparing an injectable or implantable medical material or article comprising steps of (a) preparing an emulsion comprising a hydrophobic polymer, an arylboronic acid, a continuous phase, and a discontinuous phase, wherein the hydrophobic polymer is in the discontinuous phase and the arylboronic acid is in the continuous phase, and wherein particulates comprising the hydrophobic polymer are formed in the emulsion, and (b) using the particulates for the preparation of, or as an injectable or implantable medical material or article.
Microparticles formed from a process comprising a step of preparing an emulsion comprising a hydrophobic polymer, an arylboronic acid, a continuous phase, and a discontinuous phase, wherein the hydrophobic polymer is in the discontinuous phase and the arylboronic acid is in the continuous phase, and wherein microparticles comprising the hydrophobic polymer are formed in the emulsion.
Dependencies are inferred from the claim text.