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US 8,709,488 B2Granted
Method and composition for hyperthermally treating cells
OwnerGholam A. Peymaninventor
Life of this patent
Estimating the term…
Abstract
A method and composition for hyperthermally treating tumor cells in a patient under conditions that affect tumor stem cells and tumor cells. In one embodiment, the method provides a synergistic effect with chemotherapy.
Claims20
A method to target therapy to cells in a patient in need thereof, the method comprising
- (a) administering an antibody-coated and/or drug-containing nanoparticle composition to a patient in need thereof,
- (b) thereafter in the absence of a contrast agent administering staged temperature increase thermotherapy at a target containing the antibody specific and/or drug-coated nanoparticles and exposing the target to an energy source to generate an acoustic sound in-situ, the thermotherapy administered under conditions sufficient to result in targeted therapy to cells in the patient.
A method to target therapy to cells in a patient in need thereof, the method comprising
- (a) administering an antibody-coated and/or drug-containing nanoparticle composition to a patient in need thereof,
- (b) thereafter administering staged temperature increase thermotherapy at a target containing the antibody specific and/or drug-coated nanoparticles and exposing the target to an energy source to generate an acoustic sound in-situ, the thermotherapy administered under conditions sufficient to result in targeted therapy to cells in the patient.
Dependencies are inferred from the claim text.