Combination of a microorganism and a phytosphingosine derivative, composition, methods of use

A composition comprising, in a physiologically acceptable medium, at least one phytosphingosine salicylate derivative and at least one lysate of at least one microorganism of the genus Bifidobacterium, wherein said at least one phytosphingosine salicylate derivative is at least one compound of the formula:

• in which:
• R represents:
• a hydrogen atom,
• a saturated or unsaturated, linear or branched C1 to C49 aliphatic radical, optionally substituted with a hydroxyl radical, or
• a group Y—O(CaHb)m—,
• with a being an integer from 7 to 50, b an integer from 10 to 100, m is 0 or 1 and Y represents H or a C14-C22 fatty acid having the formula:
• —CO—(CxHyZz)CH3,
• with Z being —OH or an epoxy oxygen, x an integer from 12 to 20, y an integer from 20 to 40, and z is 0 or an integer from 1 to 4;
• R1 represents a saturated or unsaturated, linear or branched C8 to C28 aliphatic radical, optionally substituted with a hydroxyl radical, and
• R2 represents H, a phosphate radical, a sulphate radical or a sugar,
• wherein the at least one microorganism of the genus Bifidobacterium comprises Bifidobacterium longum, and
• wherein the phytosphingosine salicylate derivative is present in a proportion of at least 0.0001% expressed as dry weight, relative to the total weight of the composition.