Film-forming resins as a carrier for topical application of pharmacologically active agents
AssigneeJaleva Pharmaceuticals, LLC
InventorAlex Battaglia
Life of this patent
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Abstract
The invention provides a biological dressing for treatment of a dermatological disease comprised of one or more resins or other film-forming agents, a topically acceptable volatile solvent, and a pharmacologically active agent. The combined one or more resins are present in a suitable amount such that the composition, when the solvent evaporates, will dry to form a solid coating that sticks to the skin, nail or mucosal membrane to which the composition is applied, and maintain the pharmacologically active agent over a sustained period of time in contact with sites on the skin or mucosal membranes exhibiting symptoms of the disease. Methods are provided for treating symptoms of dermatological diseases with such a pharmacological composition.
Claims20
A pharmacological composition comprising:
- a) 1%-15% benzoin;
- b) 0.01%-5% chlorhexidine gluconate;
- c) 70% to 98% of a topically acceptable volatile solvent for the resin and the chlorhexidine selected from the group consisting of ethanol, propanol, isopropanol, ethyl acetate, and n-propyl acetate;
- and d) water.
A pharmacological composition comprising:
- a) tincture of 1%-15% benzoin;
- b) 0.01%-5% chlorhexidine gluconate;
- c) 70-85% ethanol;
- and d) water.
A method of treating a subject having or at risk of having a microbial infection comprising contacting a skin or mucosal surface of the subject having the microbial infection with a pharmacological composition comprising:
- (a) 1%-15% benzoin;
- (b) 0.01%-5% chlorhexidine gluconate;
- (c) 70% to 98% of a topically acceptable volatile solvent selected from the group consisting of ethanol, propanol, isopropanol, ethyl acetate, and n-propyl acetate;
- and
- (d) water.
A pharmacological composition comprising:
- a) 1%-15% benzoin;
- b) 0.01%-5% chlorhexidine gluconate;
- c) 70% to 98% of a topically acceptable volatile solvent for the resin and the chlorhexidine;
- and d) water.
A method of treating a subject having or at risk of having a microbial infection comprising contacting a skin or mucosal surface of the subject having the microbial infection with a pharmacological composition comprising:
- (a) 1%-15% benzoin;
- (b) 0.01%-5% chlorhexidine gluconate;
- (c) 70% to 98% of a topically acceptable volatile solvent;
- and
- (d) water.
Dependencies are inferred from the claim text.