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US 8,709,426 B2Granted
Nucleotide sequence coding for variable regions of β chains of human T lymphocyte receptors, corresponding peptide segments and the diagnostic and therapeutic uses
AssigneeAventis Pharma S.A.
InventorsThierry Hercend, Frederic Triebel, Sergio Roman-Roman, Laurent Ferradini
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Abstract
The present invention relates to new nucleotide sequences coding for variable regions of β chains of human T lymphocyte receptors, corresponding peptide segments and the diagnostic and therapeutic uses.
Claims11
An isolated antibody, or an antigen binding fragment thereof, directed against an antigenic determinant of a Vβ peptide encoded by a nucleic acid sequence selected from the group consisting of:
- nucleotides 54 to 395 of SEQ ID NO:
- 3,
- nucleotides 18 to 329 of SEQ ID NO:
- 4, and
- nucleotides 28 to 366 of SEQ ID NO:
- 5,
- wherein the antibody, or antigen binding fragment thereof, specifically binds to the Vβ peptide.
4 more elements
Dependencies are inferred from the claim text.