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US 8,709,424 B2Granted
Anti-GITR antibodies
AssigneeMerck Sharp & Dohme Corp.
InventorsXiao Min Schebye, Grigori P. Ermakov, Douglas J. Hodges, Leonard G. Presta
Life of this patent
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Abstract
Antibodies to human GITR are provided, as well as uses thereof, e.g., in treatment of proliferative and immune disorders.
Claims6
A binding compound that binds to human GITR comprising:
- a) an antibody light chain variable domain, or antigen binding fragment thereof, having three CDR sequences selected from the group consisting of SEQ ID NOs:
- 56, 67, and 78;
- and
- b) an antibody heavy chain variable domain, or antigen binding fragment thereof, having three CDR sequences selected from the group consisting of SEQ ID NOs:
- 23, 34, and 45.
2 more elements
Dependencies are inferred from the claim text.