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US 8,709,417 B2Granted
Combination immunotherapy for the treatment of cancer
AssigneesMemorial Sloan Kettering Cancer Center, Board of Regents
InventorsJames Allison, Padmanee Sharma, Sergio A. Quezada, Tihui Fu
Life of this patent
Estimating the term…
Abstract
Agonists to ICOS in combination with a blocking agent to a T cell inhibitory receptor (e.g., CTLA-4, PD-I, etc.) are demonstrated herein to be useful for the treatment of tumors.
Claims6
A method of treating cancer in a patient comprising administering to the patient simultaneously or sequentially a blocking anti-CLTA-4 antibody and an ICOS ligand (ICOS-L).
Dependencies are inferred from the claim text.