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US 8,709,386 B2Granted
Method of making and using an alpha-glucanase composition to reduce or remove biofilm
AssigneeDanisco US Inc.
InventorsSteven Kim, Suzanne Lantz, Michael Pepsin
Life of this patent
Estimating the term…
Abstract
Isolated α-glucanases from Hypocrea tawa, Trichoderma reesei, and Trichoderma konilangbra are described, as well as oral care compositions containing the same. The oral care composition may be employed to prevent or reduce dental plaque.
Claims9
A method for making an oral care composition for the removal of biofilms, comprising:
- admixing an α-glucanase having an amino acid sequence that is at least 90% identical to that of mature Trichoderma reesei α-glucanase (amino acid residues 38-622 of SEQ ID NO:
- 2) with an orally acceptable excipient to make an oral care composition for the, thereby removing biofilms.
A method for removing biofilms, comprising:
- contacting a composition comprising an α-glucanase having an amino acid sequence that is at least 90% identical to that of mature Trichoderma reesei α-glucanase (amino acid residues 38-622 of SEQ ID NO:
- 2) with a biofilm under conditions suitable for activity of said α-glucanase to disrupt polysaccharide components present in the biofilm, thereby removing biofilms.
Dependencies are inferred from the claim text.