US 8,709,346 B2Granted

Analysis device and an analysis apparatus using the analysis device

AssigneePanasonic Corporation

InventorsHiroshi Saiki, Masanori Tanaka

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Abstract

An analysis device includes a separation chamber, a holding channel, a mixing chamber connected to the holding channel, an overflow channel connected between the holding channel and the separation chamber, a sample overflow chamber into which a sample solution remaining in the separation chamber is discharged, and a joint channel connecting the separation chamber and the sample overflow chamber. After the separated solution component fills the overflow channel with priority, a separated solid component is transferred to the holding channel via the overflow channel, and a predetermined amount of the solid component is measured. The solid component in the holding channel is transferred to the mixing chamber by a centrifugal force, and simultaneously, the sample solution remaining in the separation chamber is discharged to the sample overflow chamber by the siphon effect of the joint channel.

Claims12

Dependent claims

An analysis device for storing and transferring a sample solution to be analyzed, said device comprising:

a fluid storage chamber configured to have the sample solution injected and stored therein;
a separation chamber configured to separate the sample solution into a solution component and a solid component by applying a centrifugal force generated by rotation of the analysis device;
a holding channel configured to have a capillary force for holding a part of the solution component separated by the separation chamber;
a first joint channel that joins the separation chamber and the holding channel, the first joint channel configured to have a capillary force;
an air hole disposed on a boundary region between the first joint channel and the holding channel;
a measurement cell configured to hold the part of the solution component separated by the separation chamber and transferred from the holding channel, the solution component being transferred by an external force;
a sample overflow chamber positioned outwardly of the separation chamber with respect to an axial center of the analysis device when the analysis device is rotated around the axial center;
and
a second joint channel configured and arranged to collect the sample solution other than the part of the solution component into the sample overflow chamber, the second joint channel configured to have a capillary force, and the second joint channel having a siphon structure with a bend portion which is arranged so as to be positioned inwardly of a solution level of the sample solution stored in the separation chamber with respect to the axial center of the analysis device,
wherein the solution level corresponds to a predetermined solution level of the sample solution when held in the separation chamber.

7 more elements

An analysis device for storing and transferring a sample solution to be analyzed, said device comprising:

a fluid storage chamber configured to have the sample solution injected and stored therein;
a separation chamber configured to separate the sample solution into a solution component and a solid component by applying a centrifugal force generated by rotation of the analysis device;
a holding channel configured to have a capillary force for holding a part of the solid component separated by the separation chamber;
a first joint channel that joins the separation chamber and the holding channel, the first joint channel configured to have a capillary force;
an air hole disposed on a boundary region between the first joint channel and the holding channel;
a measurement cell configured to hold the part of the solid component separated by the separation chamber and transferred from the holding channel, the solid component being transferred by an external force;
a sample overflow chamber positioned outwardly of the separation chamber with respect to an axial center of the analysis device when the analysis device is rotated around the axial center;
and
a second joint channel configured and arranged to collect the sample solution other than the part of the solid component into the sample overflow chamber, the second joint channel configured to have a capillary force, and the second joint channel having a siphon structure with a bend portion which is arranged so as to be positioned inwardly of a solution level of the sample solution stored in the separation chamber with respect to the axial center of analysis device,
wherein the solution level corresponds to a predetermined solution level of the sample solution when held in the separation chamber.

7 more elements

Dependencies are inferred from the claim text.

Facts

Application: 12/945,215Filed 12 Nov 2010 · division
Priority: 28 Mar 2008
Published: US 2011/0058985 A110 Mar 2011
Granted: 29 Apr 2014
Term ends: Not estimatedThe source records don’t support an estimate.

Classification21 codes

G01N 33/491
Blood: by separating the blood components
B01L 3/50273
By integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g.…
G01N 21/07
Cuvette constructions: centrifugal type cuvettes
G01N 21/82
By observing the effect on a chemical indicator: producing a precipitate or turbidity

Family

Application12/058,226Parent of this division · filed 28 Mar 2008
US 2011/0058985 A1Pre-grant publication · published 10 Mar 2011
US 7,854,893 B2Parent of this division
US 2009/0246082 A1Published application
US 8,709,346 B2This patent

From the US filing history. Foreign family members aren’t listed.