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US 8,709,070 B2Granted
Bioabsorbable scaffold with particles providing delayed acceleration of degradation
AssigneeAbbott Cardiovascular Systems Inc.
InventorsYunbing Wang, James Oberhauser
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Abstract
Methods of controlling the degradation profile of a biodegradable stent scaffolding are disclosed. A bioabsorbable scaffold having a plurality of particles incorporated into the scaffolding that accelerate the absorption of the scaffolding after an induction time during degradation is disclosed.
Claims8
A stent comprising:
- a scaffolding made of poly L-lactide (PLLA);
- a plurality of particles dispersed throughout the scaffolding,
- wherein the particles comprise L-lactide monomer that is not polymerized or chemically bound to other molecules said L-lactide monomer encapsulated by a surface-eroding polymer,
- wherein when the scaffolding is exposed to moisture the surface-eroding polymer prevents contact of the L-lactide with the moisture for a selected induction time and after the selected induction time the L-lactide accelerates degradation of the PLLA of the scaffolding.
1 more element
Dependencies are inferred from the claim text.