Implantable materials having engineered surfaces comprising a pattern of features and method of making same
AssigneeAdvanced Bio Prosthetic Surfaces, Ltd.
InventorsJulio C. Palmaz, Eugene A. Sprague
Life of this patent
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Abstract
Implantable materials having defined patterns of affinity regions for binding endothelial cells and providing for directed endothelial cell migration across the surface of the material. The affinity regions include photochemically altered regions of a material surface and physical members patterned on the material surface that exhibit a greater affinity for endothelial cell binding and migration than the remaining regions of the material surface.
Claims8
An implantable, biocompatible material, comprising at least one original surface, wherein the at least one original surface has a patterned array of three-dimensional features on the at least one original surface having a height above the at least one original surface between about 0.1 μ to about 3.0 μ and having surface energy different than the at least one original surface of the biocompatible material, and wherein the plurality of three-dimensional features comprise a shape selected from the group consisting of a rectangular, triangular, circular, or square shape and increase the rate of endothelial cell binding, proliferation, and migration across the at least one original surface of the biocompatible material.
Dependencies are inferred from the claim text.