Laser system for non ablative treatment of mucosa tissue

A method for non-ablative treatment of mucosa tissue by using a laser system comprising a laser source for generating a laser beam, a control unit and a hand piece, wherein the laser beam is manually guided onto a target area on the mucosa tissue, wherein a wavelength (λ) of the laser beam is in a range from above 1.9 μm to 11.0 μm inclusive, the method comprising:

• Generating with the laser source under control of the control unit the laser beam in at least one pulse sequence, wherein said at least one pulse sequence consists of a number of single pulses with a pulse duration (tp) in a range from 1.0 μs, inclusive, to 1.0 sec, inclusive, wherein the number of single pulses is in a single pulse range of two to fifteen;
• wherein the single pulses each provide on the target area of the mucosa tissue a fluence in a fluence range from 0.2 J/cm2, inclusive;
• wherein a sequence duration (ts) of said at least one pulse sequence is in a range from 50.0 ms, inclusive, to 1,000.0 ms, inclusive;
• Adjusting, in said at least one pulse sequence, the fluence within said fluence range and the number of said single pulses within said single pulse range and applying said at least one pulse sequence to the mucosa tissue such that heat is deposited into the mucosa tissue in a controlled manner to a depth of at least 100 μm and that the mucosa tissue is heated within said depth to a range from 50 degrees Celsius to 70 degrees Celsius.