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AssigneeImpactcare ApS
InventorsPer Møller, Anette Alsted Rasmussen
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An article to be inserted in a human or animal body cavity, use of the article and preparation thereof. The article has a biologically inhibiting arrangement of electrically connected electrode materials in direct contact with each other on one or more surfaces of the article. The arrangement includes as electrode materials a metallic anode material and a cathode material, where the potential of the cathode material is higher than the potential of the anode material. The cathode material is an electrically conductive material selected among certain non-metallic materials. The arrangement provided on the article releases biological inhibiting ions of the metallic anode material or complexes of such ions when the biologically inhibiting arrangement is contacted with a body fluid. The article can be designed with a controlled release rate suitable for the purpose in question for example an initial high rate of ion release after insertion of a catheter to combat bacteria introduced during the insertion followed by a prolonged release at a lower rate to maintain a low level of bacteria.
The article to be inserted in a human or animal body cavity having a biologically inhibiting arrangement of electrically connected electrode materials present on one or more surfaces of the article as added electrode materials other than the material of the article itself, which arrangement as electrode materials includes at least one or a plurality of metallic anode materials and an electrically conductive nonmetallic cathode materials in direct contact with each other so that when the article is inserted in the body it forms a galvanic couple in the presence of an electrolyte, wherein the arrangement of electrode materials is configured to provide a potential of the cathode material that is higher than the potential of the anode material and a value of the difference Δp between the respective potentials of the anode material (pA) and the cathode material (pc) that is at least 25 mV, so that the arrangement has an in vivo action which releases biological inhibiting ions of the metallic anode material or complexes of such ions when the biologically inhibiting arrangement is contacted with an electrolyte comprising a body fluid, wherein said conductive nonmetallic cathode material is selected from the group consisting of graphite, nitrides, borides, carbides, mixed nitrides, silicides, oxides having a spinel structure of the formula XY2O4 wherein X is divalent Mg, Zn, Fe or Mn and Y is trivalent Al, Fe, Mn or Cr, conductive polymers and combinations of two or more thereof.
The article to be inserted in a human or animal body cavity having a biologically inhibiting arrangement of electrically connected electrode materials present on one or more surfaces of the article as added electrode materials other than the material of the article itself, which arrangement as electrode materials includes an anode material of Ag and a cathode material of graphite in direct contact with each other so that when the article is inserted in the body it forms a galvanic couple in the presence of an electrolyte, wherein the arrangement of electrode materials is configured to provide a potential of the cathode material that is higher than the potential of the anode material and a value difference (Δp) between the respective potentials of the anode material (pA) and the cathode material (pc) that is at least 25 mV, so that the arrangement has an in vivo action which releases biological inhibiting ions of the Ag anode material or complexes of such ions when the biologically inhibiting arrangement is contacted with an electrolyte comprising a body fluid.
An article to be inserted in a human or animal body cavity having a biologically inhibiting arrangement of electrically connected electrode materials present on one or more surfaces of the article as added electrode materials other than the material of the article itself, which arrangement as electrode materials includes one or a plurality of metallic anode materials and electrically conductive nonmetallic cathode materials, wherein the anode and cathode materials are in direct contact with each other so that when the article is inserted in the body it forms a galvanic couple in the presence of an electrolyte, with the anode and cathode materials having diameter sizes of between 1 nm and 10 μm, wherein the arrangement of electrode materials is configured to provide a potential of the cathode material that is higher than the potential of the anode material and a value of the difference Δp between the respective potentials of the anode material (pA) and the cathode material (pc) that is at least 25 mV, so that the arrangement has an in vivo action which releases biological inhibiting ions of the metallic anode material or complexes of such ions when the biologically inhibiting arrangement is contacted with an electrolyte comprising a body fluid, wherein said conductive nonmetallic cathode material is selected from the group consisting of nitrides, borides, graphite, carbides, mixed nitrides, silicides, oxides having a spinel structure of the formula XY2O4 wherein X is divalent Mg, Zn, Fe or Mn and Y is trivalent Al, Fe, Mn or Cr, conductive polymers and combinations of two or more thereof.
Dependencies are inferred from the claim text.