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US 8,704,167 B2Granted
Mass spectrometry analysis of microorganisms in samples
AssigneePurdue Research Foundation
InventorsRobert Graham Cooks, Ahmed Mohamed Hamid, Alan Keith Jarmusch, Zheng Ouyang
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Abstract
The invention generally relates to systems and methods for mass spectrometry analysis of microorganisms in samples.
Claims18
A method for analyzing a microorganism from a sample comprising:
- contacting a sample comprising a microorganism to a porous material, wherein the porous material is kept separate from a flow of solvent;
- applying high voltage to the porous material to generate ions of the microorganism that are expelled from the porous material;
- and
- analyzing the expelled ions, thereby analyzing the microorganism.
1 more element
A method for identifying an unknown microorganism in a sample, the method comprising:
- contacting a sample comprising an unknown microorganism to a porous material, wherein the porous material is kept separate from a flow of solvent
- generating one or more mass spectra of the unknown microorganism using a mass spectrometer;
- comparing the one or more mass spectra of the unknown microorganism to a database that comprises mass spectra of known organisms, thereby identifying the organism.
Dependencies are inferred from the claim text.