# US 8,698,031 B2 · Separation and manipulation of a chiral object > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 8,698,031 B2 - Document ID: US8698031B2 - Status: Granted - Kind: B2 - Application number: 12/142,545 - Filed: 2008-06-19 - Published: 2008-11-06 - Granted: 2014-04-15 - Earliest claimed: 2007-04-17 - Assignees: Dynamic Connections, LLC - Applicants: Osman Kibar; Mirianas Chachisvilis; Eugene Tu; Thomas H. Marsilje - Inventors: Osman Kibar; Mirianas Chachisvilis; Eugene Tu; Thomas H. Marsilje - Web page: https://patentgrep.com/patent/US8698031B2 ## CPC - C07C 303/44: Separation; Purification - B03C 1/24: with material carried by travelling fields - B03C 7/026: {using travelling or oscillating electric fields} - C07B 57/00: Separation of optically-active compounds - C07C 201/16: Separation; Purification; Stabilisation; Use of additives - Y10T 436/143333: Saccharide [e.g., DNA, etc.] - Y10T 436/25375: Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.] - C07C: ACYCLIC OR CARBOCYCLIC COMPOUNDS - B03C: MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS (separating isotopes B01D59/00; combinations of magnetic or electrostatic separation with separation of solids by other means B03B, B07B) - C07B: GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR (preparation of carboxylic acid esters by telomerisation C07C67/47; telomerisation C08F) - Y10T: TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION ## Abstract Among other things, for use in directional motion of chiral objects in a mixture, a field is applied across the chamber and is rotating relative to the chamber to cause rotation of the chiral objects. The rotation of the objects causes them to move directionally based on their chirality. The method applies to sugars, proteins, and peptides, among other things, and can be used in a wide variety of applications. ## Claims ### Claim 1 A method comprising applying across a chamber a field having a field direction that rotates relative to the chamber to cause spin rotation of chiral objects in a mixture in the chamber, each chiral object's axis of rotation lying within the chiral object itself, the spin rotations of the chiral objects causing a net directional motion of the chiral objects along the axis of rotation of the field, and effecting a step of an application or process using a result of the net directional motion of the chiral objects. ### Claim 2 (depends on 1) The method of claim 1 in which the chiral objects comprise sugar molecules. ### Claim 3 (depends on 2) The method of claim 2 in which the sugar molecules comprise at least one of monosaccharides, disaccharides, oligosaccharides, or polysaccharides (glycans). ### Claim 4 (depends on 1) The method of claim 1 in which the chiral objects comprise proteins. ### Claim 5 (depends on 1) The method of claim 1 in which the chiral objects comprise peptides. ### Claim 6 (depends on 1) The method of claim 1 in which the application or process comprises a genomics application or process. ### Claim 7 (depends on 1) The method of claim 1 in which the application or process comprises a proteomics application or process. ### Claim 8 (depends on 1) The method of claim 1 also including in which the application or process comprises a glycomics application or process. ### Claim 9 (depends on 1) The method of claim 1 also including in which the application or process comprises a chemical manufacturing application or process. ### Claim 10 (depends on 1) The method of claim 1 also including in which the application or process comprises a food processing application or process. ### Claim 11 (depends on 1) The method of claim 1 also including in which the application or process comprises a forensics application or process. ### Claim 12 (depends on 1) The method of claim 1 also including in which the application or process comprises an academic research application or process. ### Claim 13 (depends on 1) The method of claim 1 also including in which the application or process comprises a solvent purification application or process. ### Claim 14 (depends on 1) The method of claim 1 also including in which the application or process comprises an asymmetric synthesis application or process. ### Claim 15 (depends on 1) The method of claim 1 in which a product outcome of a chemical reaction is purified. ### Claim 16 (depends on 1) The method of claim 1 in which a product outcome of a chemical reaction is quantified. ### Claim 17 (depends on 1) The method of claim 1 in which a product outcome of a chemical reaction is identified. ### Claim 18 (depends on 15, 16) The method of claim 15, 16, or 17 in which a product outcome of a chemical reaction comprises a non-racemic product mixture. ### Claim 19 (depends on 15, 16) The method of claim 15, 16, or 17 in which a product outcome of a chemical reaction comprises a racemic product mixture. ### Claim 20 (depends on 1) The method of claim 1 in which the chiral objects comprise achiral molecules that have chiral labels attached. ### Claim 21 (depends on 20) The method of claim 20 in which the achiral molecules comprise lipids.