Heteroatom containing substituted fatty acids
AssigneeComplexa, Inc.
InventorRaymond A. Miller
Life of this patent
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Abstract
Activated fatty acids, pharmaceutical compositions including activated fatty acids, methods for using activated fatty acids to treat a variety of diseases, and methods for preparing activated fatty acids are provided herein.
Claims16
An activated fatty acid or a pharmaceutically acceptable salt thereof comprising an unsaturated or polyunsaturated aliphatic chain having one or more heteroatoms positioned anywhere within the aliphatic chain and one or more electron withdrawing groups positioned immediately adjacent to the heteroatom or carbon-carbon double bond or immediately adjacent to a carbon immediately adjacent to the heteroatom or carbon-carbon double bond;
- wherein the at least one of the one or more electron withdrawing groups is selected from a group consisting of sulfoxides (—SOR), sulfonyls (—SO2R), sulfonic acids (—SO3H), 1°, 2°, and 3° ammonium (—NR3+), or nitro (—NO2), wherein R is selected from the group consisting of hydrogen, methyl, and C2-C6 alkyl.
A pharmaceutical composition comprising:
- an unsaturated or polyunsaturated aliphatic chain or a pharmaceutically acceptable salt thereof having one or more heteroatoms positioned anywhere within the aliphatic chain and one or more electron withdrawing groups positioned immediately adjacent to the heteroatom or carbon-carbon double bond or immediately adjacent to a carbon immediately adjacent to the heteroatom or carbon-carbon double bond, wherein the at least one of the one or more electron withdrawing groups is selected from a group consisting of sulfoxides (—SOR), sulfonyls (—SO2R), sulfonic acids (—SO3H), 1°, 2°, and 3° ammonium (—NR3+), or nitro (—NO2), wherein R is selected from the group consisting of hydrogen, methyl, and C2-C6 alkyl;
- and a pharmaceutically acceptable carrier, excipient, or combinations thereof.
Dependencies are inferred from the claim text.