Cosmetic and/or pharmaceutical composition comprising a peptidic hydrolyzate that can reinforce the barrier function
AssigneeISP Investments Inc.
InventorsClaude Dal Farra, Nouha Domloge, Jean-Marie Botto
Life of this patent
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Abstract
A peptidic hydrolyzate enriched in bioactive peptide, capable of reinforcing the skin barrier function and stimulating epidermal differentiation is described. Additionally, a cosmetic and/or pharmaceutical composition that includes a physiologically acceptable medium and the peptidic hydrolyzate as active principle are described. The cosmetic composition activates the HMG-CoA reductase in the cutaneous cells and treats the cutaneous signs of aging and photo-aging.
Claims18
A peptidic hydrolyzate comprising:
- one or more bioactive peptide each with a molecular weight of less than 6 kDa, each bioactive peptide or combination thereof reinforcing the barrier function of the epidermis, said bioactive peptide comprising 4 to 6 amino acids comprising at least one glycine residue, one leucine residue, and one glutamic acid residue, wherein said peptidic hydrolyzate is isolated from the hydrolysis of plants selected from the group consisting of einkorn (Triticum monococum), potato (Solanum tuberosum), corn (Zea mayz L.), pea (Pisum sativum) or from the hydrolysis of yeasts of the Saccharomyces genus.
A cosmetic composition comprising:
- a physiologically acceptable medium;
- and
- a peptidic hydrolyzate in said medium, the peptide hydrolyzate comprising one or more bioactive peptide each with a molecular weight of less than 6 kDa, each bioactive peptide or combination thereof reinforcing the barrier function of the epidermis, said bioactive peptide comprising 4 to 6 amino acids comprising at least one glycine residue, one leucine residue, and one glutamic acid residue, said peptidic hydrolyzate is isolated from the hydrolysis of plants selected from the group consisting of einkorn (Triticum monococum), potato (Solanum tuberosum), corn (Zea mayz L.), pea (Pisum sativum) or from the hydrolysis of yeasts of the Saccharomyces genus;
- wherein the peptidic hydrolyzate is present in a quantity representing from 0.0001% to 20% of the total weight of the composition.
A cosmetic composition comprising:
- an effective quantity of a peptidic hydrolyzate as an active principle activating 3-hydroxy-3-methylglutaryl-Coenzyme A (HMG-CoA) reductase, said peptidic hydrolyzate comprising a bioactive peptide reinforcing the barrier function of the epidermis, said bioactive peptide containing 4 to 6 amino acids including at least one glycine residue, one leucine residue, and one glutamic acid residue.
A method for treating the cutaneous manifestations of aging and/or photo-aging, the method comprising:
- providing a composition comprising an effective quantity of a peptidic hydrolyzate, said peptidic hydrolyzate comprising one or more bioactive peptide each with a molecular weight of less than 6 kDa, each bioactive peptide or combination thereof reinforcing the barrier function of the epidermis, said bioactive peptide comprising 4 to 6 amino acids comprising at least one glycine residue, one leucine residue, and one glutamic acid residue wherein said peptidic hydrolyzate is isolated from the hydrolysis of plants selected from the group consisting of einkorn (Triticum monococum), potato (Solanum tuberosum), corn (Zea mayz L.), pea (Pisum sativum) or from the hydrolysis of yeasts of the Saccharomyces genus;
- and
- topically applying the composition to the skin or epithelial appendages to be treated.
A method for reinforcing the barrier function of the epidermis, the method comprising:
- providing a composition comprising a peptidic hydrolyzate isolated from the hydrolysis of plants selected from the group consisting of einkorn (Triticum monococum), potato (Solanum tuberosum), corn (Zea mayz L.), pea (Pisum sativum), soy (Glycine Max. L.), or yeast (Saccharomyces cerevisiae), said peptidic hydrolyzate comprising one or more bioactive peptide each with a molecular weight of less than 6 kDa, each bioactive peptide or combination thereof comprising 4 to 6 amino acids comprising at least one glycine residue, one leucine residue, and one glutamic acid residue;
- as an active principle activating HMG-CoA reductase;
- and
- topically applying the composition to the skin or epithelial appendages to be treated.
Dependencies are inferred from the claim text.