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US 8,669,226 B2Granted
Antimicrobial compositions and methods of use thereof
AssigneeMorehouse School of Medicine
InventorsVincent Craig Bond, Michael Powell, Ming Bo Huang, Syed Ali, Martin Neville Shelton
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Abstract
The present application discloses a method for treating microbial infection using an antimicrobial composition comprises antimicrobial peptide which contains at least one VGFPV motif.
Claims9
A method of treating Escherichia coli infection, comprising:
- administering to a subject in need thereof an effective amount of an antibacterial peptide comprising the amino acid sequence of SEQ ID NO:
- 3.
A method of treating Escherichia coli infection, comprising:
- administering to a subject in need thereof an effective amount of an in vivo polynucleotide expression vector that encodes an antibacterial peptide comprising the amino acid sequence of SEQ ID NO:
- 3,
- wherein said in vivo expression vector expresses said antibacterial peptide in said subject.
A method of treating Escherichia coli infection, comprising:
- administering to a subject in need thereof an effective amount of a bacteria phage displaying an antibacterial peptide on its surface,
- wherein said antibacterial peptide comprises the amino acid sequence of SEQ ID NO:
- 3.
Dependencies are inferred from the claim text.