Back to results
US 8,669,048 B2Granted
Pluripotent cell lines and methods of use thereof
AssigneeParkinson's Institute
InventorsRenee Ann Reijo Pera, J. William Langston, Birgitt Schüle, Theodore D. Palmer
Life of this patent
Estimating the term…
Abstract
Methods of generating cell lines with a sequence variation or copy number variation of a gene of interest, methods of use thereof, and cell lines with a sequence variation or copy number variation of a gene of interest are provided.
Claims16
A method of determining whether an agent is useful in the treatment of Parkinson's disease or Parkinson's-related disease, the method comprising:
- a) contacting dopaminergic cells produced from induced pluripotent stem cells derived from a patient with Parkinson's disease or Parkinson's-like disease with an agent;
- b) detecting a response to said agent in said cells;
- and
- c) determining whether the agent is useful in the treatment based on the detected response.
1 more element
Dependencies are inferred from the claim text.