Implantable biomedical devices on bioresorbable substrates

A method for administering an implantable biomedical device, said method comprising:

• providing the implantable biomedical device comprising:
• a bioresorbable substrate;
• an electronic device comprising a plurality of inorganic semiconductor components supported by said bioresorbable substrate, wherein at least one of said inorganic semiconductor components has at least one physical dimension less than or equal to 100 microns;
• and
• a barrier layer encapsulating at least a portion of said inorganic semiconductor components;
• contacting said implantable biomedical device with a target tissue in a biological environment;
• and
• at least partially resorbing said bioresorbable substrate in said biological environment, thereby establishing conformal contact between said implantable biomedical device and said target tissue in said biological environment.

A method of actuating a target tissue or sensing a parameter associated with the target tissue in a biological environment, said method comprising:

• providing an implantable biomedical device comprising:
• a bioresorbable substrate;
• an electronic device comprising a plurality of inorganic semiconductor components supported by said bioresorbable substrate, wherein at least one of said inorganic semiconductor components has at least one physical dimension less than or equal to 100 microns;
• and
• a barrier layer encapsulating at least a portion of said inorganic semiconductor components;
• contacting said implantable biomedical device with the target tissue in a biological environment;
• at least partially resorbing said bioresorbable substrate in said biological environment, thereby establishing conformal contact between said implantable biomedical device and said target tissue in said biological environment;
• and
• actuating the target tissue or sensing the parameter associated with the target tissue that is in conformal contact with the implantable biomedical device.

An implantable biomedical device for actuating a target tissue or sensing a parameter associated with the target tissue in a biological environment, said device comprising:

• an electrode array comprising a plurality of individually addressable inorganic semiconductor components, wherein each inorganic semiconductor component has at least one physical dimension less than or equal to 100 microns;
• a barrier layer having a mesh structure, wherein said barrier layer at least partially supports said electrode array;
• and
• a bioresorbable substrate supporting said electrode array, said barrier layer or both of said electrode array and said barrier layer;
• wherein upon contact with said biological environment said bioresorbable substrate is at least partially resorbed, thereby establishing conformal contact between said electrode array and said target tissue in said biological environment.

A method for actuating a target tissue or sensing a parameter associated with the target tissue in a biological environment, the method comprising:

• providing an implantable biomedical device comprising:
• an electrode array comprising a plurality of individually addressable inorganic semiconductor components, wherein each inorganic semiconductor component has at least one physical dimension less than or equal to 100 microns;
• a barrier layer having a mesh structure, wherein said barrier layer at least partially supports said electrode array;
• and
• a bioresorbable substrate supporting said electrode array, said barrier layer or both of said electrode array and said barrier layer;
• contacting said implantable biomedical device with the target tissue in a biological environment;
• wherein upon contact with said biological environment said bioresorbable substrate is at least partially resorbed, thereby establishing conformal contact between said electrode array and said target tissue in said biological environment;
• and
• actuating the target tissue or sensing the parameter associated with the target tissue that is in conformal contact with the implantable biomedical device.