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US 8,652,464 B2Granted
Method of treatment using nanoparticulate compositions having lysozyme as a surface stabilizer
AssigneeAlkermes Pharma Ireland Limited
InventorsChristian F. Wertz, Niels P. Ryde
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Abstract
The present invention is directed to nanoparticulate active agent compositions comprising lysozyme as a surface stabilizer. Also encompassed by the invention are pharmaceutical compositions comprising a nanoparticulate active agent composition of the invention and methods of making and using such nanoparticulate and pharmaceutical compositions.
Claims21
A method of treating a subject in need comprising administering or applying a nanoparticulate active agent composition comprising:
- (a) at least one active agent having an effective average particle size of less than about 2000 nm;
- and
- (b) lysozyme adsorbed on or associated with the surface of the active agent.
Dependencies are inferred from the claim text.