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US 8,647,407 B2Granted
Method of fabricating indium-111 radioactive isotope
AssigneeInstitute of Nuclear Energy Research, Atomic Energy Council
InventorsWuu-Jyh Lin, Chien-Hsin Lu, Jenn-Tzong Chen, Sun-Rong Hwang, Ying-Chieh Wang
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Abstract
The present invention provides a method for fabricating an indium(In)-111 radioactive isotope. A target of cadmium(Cd)-112 is processed through steps of dissolving with heat, absorbing, washing, desorbing and drying for obtaining the In-111 radioactive isotope. Thus, chemical separation is coordinated with the target for fabricating the In-111 radioactive isotope with high efficiency and low cost for production procedure.
Claims6
A method of fabricating an indium(In)-111 radioactive isotope, comprising the steps of:
- (a) admixing a first bromic acid solution having a molar concentration of 8N with a target having a surface of cadmium(Cd)-112 in a container, wherein said target having a surface of Cd-112 is proton irradiated to produce a proton irradiated target;
- placing said proton irradiated target onto a heating plate which elevates temperature and compresses the proton irradiated target between the heating plate and a pressing unit, all arranged in the container, so as to be dissolved to obtain a solution of In-111 and Cd-112;
- (b) applying said solution of In-111 and Cd-112 to an ion exchange resin, wherein said In-111 is absorbed onto said resin and said Cd-112 flows through and is held in a recycling tank;
- (c) applying a second 8N bromic acid solution to said ion exchange resin to wash out In-111 and then drain a waste liquid into a waste tank;
- (d) applying a third 2N bromic acid solution to said ion exchange resin to desorb In-111 and collecting the flowthrough to obtain an In-111 semi-product liquid;
- (e) drying said In-111 semi-product liquid to obtain a product of In-111 radioactive isotope;
- and
- (f) coordinating the product of In-111 radioactive isotope with a 0.01N hydrochloric acid solution to be filtered.
5 more elements
Dependencies are inferred from the claim text.