Medical devices including polyisobutylene based polymers and derivatives thereof
AssigneeCardiac Pacemakers, Inc.
InventorsShrojalkumar Desai, G. Shantanu Reddy
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Abstract
The present invention is directed to a medical electrical lead including an insulative lead body formed, at least in part, from a polyisobutylene urethane, urea or urethane/urea copolymer. In some applications, the lead body can include at least one outer tubular insulator and/or an inner elongated member formed from a polyisobutylene urethane, urea or urethane/urea copolymer. Portions of the lead body formed form the polyisobutylene urethane, urea or urethane/urea copolymer can be either extruded or molded.
Claims26
An implantable medical lead comprising:
- an elongated lead body comprising a lumen, at least one conductor disposed within the lumen and at least one electrode operatively coupled to the conductor and disposed along the lead body, wherein the lead body has a Shore hardness from about 30A to about 75D and comprises a polyisobutylene urethane, urea or urethane/urea copolymer comprising soft polymer segments and hard polymer segments;
- wherein the soft polymer segments comprise a polyisobutylene segment and at least one additional polymer segment comprising a residue of:
- a polyether diol, a fluorinated polyether diol, a fluoropolymer diol, a polyester diol, a polyacrylate diol, a polymethacrylate diol, a polysiloxane diol, a fluorinated polysiloxane diol, or a polycarbonate diol;
- and
- wherein a weight ratio of soft segments to hard segments in the copolymer ranges from 50:50 to 90:10.
An implantable medical lead comprising:
- an elongated lead body comprising a lumen, at least one conductor disposed within the lumen and at least one electrode operatively coupled to the conductor and disposed along the lead body, wherein the lead body comprises a polyisobutylene urethane, urea or urethane/urea copolymer in each of a proximal region comprising a first Shore hardness, a middle region comprising a second Shore hardness and a distal region comprising a third Shore hardness;
- wherein the copolymer comprises soft polymer segments and hard polymer segments and wherein the soft polymer segments comprise a polyisobutylene segment and at least one additional polymer segment comprising a residue of:
- a polyether diol, a fluorinated polyether diol, a fluoropolymer diol, a polyester diol, a polyacrylate diol, a polymethacrylate diol, a polysiloxane diol, a fluorinated polysiloxane diol, or a polycarbonate diol.
An implantable medical lead comprising:
- a flexible, elongated lead body comprising an inner tubular member including at least one longitudinal lumen therethrough;
- at least one conductor extending through the at least one lumen of the inner tubular member, the conductor including an electrode having an exposed surface relative to the lead body;
- and
- at least one polymeric component connected to at least one of the lead body, conductor and electrode, the at least one polymeric component comprising a polyisobutylene urethane, urea or urethane/urea copolymer, wherein the copolymer comprises soft polymer segments and hard polymer segments and wherein the soft polymer segments comprise a polyisobutylene segment and at least one additional polymer segment comprising a residue of:
- a polyether diol, a fluorinated polyether diol, a fluoropolymer diol, a polyester diol, a polyacrylate diol, a polymethacrylate diol, a polysiloxane diol, a fluorinated polysiloxane diol, or a polycarbonate diol.
Dependencies are inferred from the claim text.