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US 8,637,466 B2Granted
Multi-arm polymeric alkanoate conjugates
AssigneeNektar Therapeutics
InventorsAntoni Kozlowski, Samuel P. McManus, Jennifer Riggs-Sauthier, Xiaoming Shen, Wen Zhang
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Abstract
Among other aspects, provided herein are multi-armed polymer conjugates comprising an alkanoate-linker, compositions comprising such conjugates, and related methods of making and administering the same. Methods of treatment employing such conjugates and related uses are also provided. The conjugates are prepared with high drug loading efficiencies.
Claims2
A multi-armed polymer conjugate having the structure:
- where n ranges from about 40 to about 300.
Dependencies are inferred from the claim text.