Methods for thermal modulation of nerves contributing to renal function
AssigneeMedtronic Ardian Luxembourg S.a.r.l.
InventorsDenise Demarais, Hanson Gifford, III
Life of this patent
Estimating the term…
Abstract
Methods and apparatus are provided for treatment of heart arrhythmia via renal neuromodulation. Such neuromodulation may effectuate irreversible electroporation or electrofusion, ablation, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential attenuation or blockade, changes in cytokine up-regulation and other conditions in target neural fibers. In some embodiments, such neuromodulation is achieved through application of an electric field. In some embodiments, such neuromodulation is achieved through application of neuromodulatory agents, of thermal energy and/or of high intensity focused ultrasound. In some embodiments, such neuromodulation is performed in a bilateral fashion.
Claims24
A method for catheter-based renal denervation, the method comprising:
- positioning a neuromodulation element within a renal blood vessel of a human patient;
- and
- ablating nerves that innervate a kidney of the patient from within the renal blood vessel via the neuromodulation element.
A method for renal nerve ablation of a human patient, the method comprising:
- intravascularly delivering a modulation device to a vicinity of a renal nerve of the patient;
- and
- thermally ablating the renal nerve from within a renal blood vessel of the patient via the modulation device.
Dependencies are inferred from the claim text.