System and method of high-frame rate, time-resolved, three-dimensional magnetic resonance angiograpy
AssigneeWisconsin Alumni Research Foundation
InventorCharles A. Mistretta
Life of this patent
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Abstract
A system and method for generating time-resolved 3D medical images of a subject includes acquiring a time series of two-dimensional (2D) data sets from a portion of the subject using a magnetic resonance imaging (MRI) system and reconstructing the time series of 2D data sets into a 2D time series of images of the subject having a given frame rate. The process also includes acquiring a time-independent, 3D volume of the portion of the subject and combining the 2D time series of images of the subject with the time-independent 3D volume of the subject to generate a set of time-dependent 3D volume images of the portion of the subject at the given frame rate.
Claims19
A magnetic resonance imaging (MRI) system comprising:
- a magnet system configured to generate a polarizing magnetic field about at least a portion of a subject arranged in the MRI system;
- a plurality of gradient coils configured to apply a gradient field to the polarizing magnetic field along each of at least three directions;
- a radio frequency (RF) system configured to apply an excitation field to the subject and acquire MR image data therefrom;
- a computer system programmed to:
- acquire a time series of two-dimensional (2D) data sets from a portion of the subject using the plurality of gradient coils and RF system;
- reconstruct the time series of 2D data sets into a 2D time series of images having a given frame rate;
- acquire a time-independent, 3D volume of at least the portion of the subject;
- and
- replicate the 2D time series of images to form 3D image frames;
- and
- multiply the 3D image frames by the time-independent 3D volume of the subject to generate a set of time-dependent 3D volume images of the portion of the subject at the given frame rate.
A method for producing time-resolved, three-dimensional (3D) volume of a subject, the method comprising the steps of:
- a) acquiring a time series of two-dimensional (2D) data sets from a portion of the subject using a magnetic resonance imaging (MRI) system;
- b) reconstructing the time series of 2D data sets into a 2D time series of images of the subject having a given frame rate;
- c) acquiring a time-independent, 3D volume of the portion of the subject;
- and
- d)i) replicating the 2D time series of images to form 3D image frames;
- and
- d)ii) multiplying the 3D image frames by the time-independent 3D volume of the subject to generate a set of time-dependent 3D volume images of the portion of the subject at the given frame rate.
A method for producing time-resolved, three-dimensional (3D) volume of a subject, the method comprising the steps of:
- a) acquiring a time series of two-dimensional (2D) data sets from a portion of the subject using a magnetic resonance imaging (MRI) system;
- b) reconstructing the time series of 2D data sets into multiple sets of 2D time series of images of the subject having a given frame rate, wherein the multiple sets of 2D time series of images are at different view angles;
- c) acquiring a time-independent, 3D volume of the portion of the subject;
- and
- d) multiplying each view angle of the 2D time series of images separately by the time-independent 3D volume of the subject to generate a set of time-dependent 3D volume images of the portion of the subject at the given frame rate.
Dependencies are inferred from the claim text.