Method of detoxifying a methyl compound
AssigneeNippon Sheet Glass Co., Ltd.
InventorsKoichiro Nakamura, Akihiro Hishinuma, Shinji Kamiya
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Abstract
It is an object of the present invention to provide a method of detoxifying a methyl compound comprising arsenic etc., effectively and systematically. The method of detoxifying a methyl compound according to the present invention is characterized in that an organic halogenated compound is reacted with a methyl compound comprising at least one element selected from the groups comprising arsenic, antimony and selenium to convert the methyl compound into more harmless substances. Furthermore, in a preferred embodiment of the method of detoxifying a methyl compound according to the present invention, the method is characterized in that the element is arsenic.
Claims14
A method of detoxifying a methyl compound, comprising:
- reacting in vitro within an aqueous solvent, an organic halogenated compound with a methyl compound in the presence of a reducing agent, wherein the reducing agent is capable of reducing at least one selected from the group consisting of arsenic, antimony and selenium, and the reducing agent is at least one selected from the group consisting of reduced glutathione (GSH), oxidized glutathione, cysteine, S-adenosyl cysteine, sulforaphane and mercaptoalcohol, wherein the methyl compound comprises arsenic, and wherein in the reaction between the organic halogenated compound with the methyl compound, the methyl compound is methylated, thereby converting the methyl compound into trimethylarsineoxide, and further converting trimethylarsineoxide into arsenobetaine in the presence of the reducing agent that is at least one selected from the group consisting of reduced glutathione (GSH), oxidized glutathione, cysteine, S-adenosyl cysteine, sulforaphane and mercaptoalcohol.
Dependencies are inferred from the claim text.