Antibacterial agents and methods of use thereof
AssigneeWisconsin Alumni Research Foundation
InventorsHelen E. Blackwell, Matthew D. Bowman, Jennifer C. O'Neill, Joseph R. Stringer
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AssigneeWisconsin Alumni Research Foundation
InventorsHelen E. Blackwell, Matthew D. Bowman, Jennifer C. O'Neill, Joseph R. Stringer
Estimating the term…
The present invention relates generally to compounds providing antibacterial therapeutic agents and preparations, and related methods of using and making antibacterial compounds. Antibacterial compounds of the present invention include chalcone, alkylpyrimidine, aminopyrimidine and cyanopyridine compounds and derivatives thereof exhibiting minimum inhibitory concentrations (MIC) similar to or less than conventional antibacterial compounds in wide use. For example, the present invention provides chalcone and cyanopyridine compounds, and derivatives thereof, exhibiting high antibacterial activities having multiple electron withdrawing group substituents, such as halogens and fluorinated alkyl groups, and optionally having hydroxyl and/or alkoxyl groups substituents.
A compound having a formula selected from the group consisting of:
A compound having a formula selected from the group consisting of:
A compound having a formula selected from the group consisting of:
Dependencies are inferred from the claim text.