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US 8,618,164 B2Granted
Treatment of pain with topical diclofenac compounds
AssigneeNuvo Research Inc.
InventorsJagat Singh, Joseph Zev Shainhouse, Bradley S. Galer, Robert Dominic King-Smith, Lisa Marie Grierson, Maria Burian, Jonathan Wilkin, Edward T. Kisak, John M. Newsam
Life of this patent
Estimating the term…
Abstract
The field involves compositions useful for pain relief, including diclofenac solution and gel formulations, in particular methods of use thereof, articles of manufacture and kits that provide novel preclinical, clinical and other information to users.
Claims8
A method for applying topical agents to a knee of a patient with pain, said method comprising:
- applying a first medication comprising a topical diclofenac preparation to an area of the knee of said patient to treat osteoarthritis of the knee of said patient, wherein the topical diclofenac preparation comprises a therapeutically effective amount of diclofenac or a pharmaceutically acceptable salt thereof, and 40-50% w/w dimethyl sulfoxide;
- waiting for the treated area to dry;
- and
- subsequently applying a second prescription medication consisting of a topical medication other than said first medication to said treated area after said treated area is dry, wherein said subsequent application occurs during a course of treatment of said patient with said topical diclofenac preparation.
1 more element
A method for applying topical agents to a knee of a patient with pain, said method comprising:
- applying a first medication comprising a topical diclofenac preparation to an area of the knee of said patient to treat osteoarthritis of the knee of said patient, wherein the topical diclofenac preparation comprises a therapeutically effective amount of diclofenac and 40-50% w/w dimethyl sulfoxide;
- waiting for the treated area to dry;
- subsequently applying a second prescription medication consisting of a topical medication other than said first medication to said treated area after said treated area is dry, wherein said subsequent application occurs during a course of treatment of said patient with said topical diclofenac preparation;
- and
- wherein said step of applying a first medication does not enhance the systemic absorption of the subsequently applied second prescription medication consisting of a topical medication other than said first medication.
2 more elements
Dependencies are inferred from the claim text.