Vesiculins
AssigneeAuckland Uniservices Limited
InventorsChristina Maree Buchanan, Garth James Smith Cooper
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Abstract
The inventions relate generally to vesiculin peptides and vesiculin peptide chains, and fragments, variants and derivatives thereof, related compositions and formulations and their preparation and use, nucleic acids encoding such vesiculin peptides and vesiculin peptide chains, and fragments, variants and derivatives thereof and related vectors and host cells, hybridomas and antibodies, and methods for the prevention and treatment of conditions, diseases and disorders that would be improved, eased, or lessened by the administration of a composition of the invention, including but not limited to glucose metabolism diseases.
Claims10
An isolated polypeptide comprising a first chain having the amino acid sequence:
- (SEQ ID NO:
- 1)
- Gly Ile Val Glu Glu Cys3 Cys4 Phe Arg Ser Cys5 Asp
- Leu Ala Leu Leu Glu Thr Tyr Cys6 Ala Thr Pro Ala
- Lys Ser Glu
- and a second chain having the amino acid sequence:
- (SEQ ID NO:
- 56)
- Ala1 Tyr Arg Pro Ser Glu Thr Leu Cys1 Gly Gly Glu
- Leu Val Asp Thr Leu Gln Phe Val Cys2 Gly Asp Arg
- Gly Phe Tyr Phe Ser Arg Pro Ala Ser Arg Val Ser,
- wherein Ala1 is either present or absent.
Dependencies are inferred from the claim text.