Method for producing sclareol
AssigneeFirmenich SA
InventorMichel Schalk
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Abstract
The present invention provides a method of producing sclareol, the method comprising contacting a particular polypeptide having a sclareol synthase activity with labdenediol diphosphate (LPP). In particular, the method may be carried out in vitro or in vivo to produce sclareol, a very useful compound in the fields of perfumery and flavoring. The present invention also provides the amino acid sequence of the polypeptide used in the method. A nucleic acid derived from Salvia sclarea and encoding the polypeptide of the invention, an expression vector containing the nucleic acid, as well as a non-human organism or a cell transformed to harbor the same nucleic acid, are also part of the present invention.
Claims9
A method for producing sclareol comprising
- a) contacting labdenediol diphosphate (LPP) with an isolated polypeptide having a sclareol synthase activity and comprising the amino acid sequence of SEQ ID NO:1;
- and
- b) optionally, isolating the sclareol produced in step a).
Dependencies are inferred from the claim text.