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US 8,617,803 B2Granted
Non-specific adsorption inhibitor, probe-bonded particles, and method for producing the same
AssigneeJsr Corporation
InventorsKouji Tamori, Eiji Takamoto
Life of this patent
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Abstract
A method for producing a non-specific adsorption inhibitor includes reacting (A) a tosylated compound of polyoxyethylene monomethyl ether with (B) a polyamine having either an amino group or imino group (—NH—), or both, in total of 3 to 12.
Claims10
A method of inhibiting non-specific adsorption to an object, comprising:
- reacting a polyoxyethylene monomethyl ether with p-toluenesulfonyl chloride in the presence of two or more amine compounds, thereby producing (A) a tosylated compound of polyoxyethylene monomethyl ether, wherein said two or more amine compounds are selected from the group consisting of trimethylamine hydrochloride, trimethylamine hydrobromide, trimethylamine hydrofluoride, trimethylamine sulfate, trimethylamine nitrate, trimethylamine phosphate, triethylamine, tripropylamine, and N,N,N′,N′-tetramethylethylenediamine;
- reacting (A) the tosylated compound of polyoxyethylene monomethyl ether with (B) a polyamine having either an amino group or an imino group, or both, in a total of 3 to 12, thereby producing a non-specific adsorption inhibitor;
- and
- treating a surface of an object with the non-specific adsorption inhibitor.
1 more element
Dependencies are inferred from the claim text.