Sustained release formulations of psychoactive drugs
AssigneeTYRX, Inc.
InventorsArikha Moses, Fatima Buevich, Satish Pulapura
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Abstract
This invention provides biodegradable, sustained-release pharmaceutical compositions of a psychoactive drug formulated with biocompatible, biodegradable tyrosine-derived polyarylates.
Claims25
A sustained-release formulation comprising a tyrosine-derived polyarylate having at least one p(DT-succinate) group and a psychoactive drug physically admixed, dissolved, dispersed, or embedded within said tyrosine-derived polyarylate, and wherein said tyrosine-derived polyarylate and said psychoactive drug form a homogeneous solid matrix, and wherein said formulation provides a burst-free, sustained release of said psychoactive drug.
A sustained-release formulation comprising a tyrosine-derived polyarylate and a psychoactive drug physically admixed, dissolved, dispersed, or embedded within said tyrosine-derived polyarylate, and wherein said tyrosine-derived polyarylate and said psychoactive drug form a homogeneous solid matrix, and wherein said formulation is prepared as a solvent-cast film or a solvent-free film.
A burst-free, sustained-release microsphere or microparticle comprising a tyrosine-derived polyarylate having at least one p(DT-succinate) group and a psychoactive drug.
Dependencies are inferred from the claim text.