Back to results
US 8,617,585 B2Granted
Intramedullary drug delivery device and method of treating bone fractures
AssigneeWarsaw Orthopedic, Inc.
InventorsScott D. Boden, Jeffrey L. Scifert, James S. Marotta
Life of this patent
Estimating the term…
Abstract
An intramedullary drug delivery device is disclosed and can be inserted within a bone canal of a bone. The intramedullary drug delivery device can include a housing. A drug delivery region can be established along the housing. Also, the drug delivery region can be configured to substantially span a fracture within the bone.
Claims26
An intramedullary drug delivery device configured to be inserted within a bone canal of a bone, comprising:
- a housing extending along an axis between a first axial end and a second axial end opposite the first axial end, the housing comprising an exterior surface, an interior lumen, an opening in the first axial end configured to receive a drug delivery tube and a guide wire hole in the second axial end configured to receive a guide wire;
- a drug delivery tube extending through the opening such that at least a portion of the drug delivery tube is positioned within the lumen, the drug delivery tube being configured to deliver a drug into the lumen;
- and
- a drug delivery region established along the housing, the drug delivery region including a proximal end and a distal end, the proximal end includes a drug delivery fenestration and the distal end includes a drug delivery fenestration, the drug delivery fenestrations being configured to provide drug delivery from the lumen through the exterior surface of the housing, wherein the drug delivery region is configured to substantially straddle a fracture within the bone such that the drug delivery fenestration on the proximal end is positioned on one side of the fracture and the drug delivery fenestration on the distal end is positioned on another side of the fracture.
1 more element
An intramedullary drug delivery device configured to be inserted within a bone canal of a bone, comprising:
- a housing extending along an axis between a first axial end and a second axial end opposite the first axial end, the housing comprising an exterior surface, an opening in the first axial end and an interior lumen;
- a drug delivery tube extending through the opening such that at least a portion of the drug delivery tube is positioned within the lumen, the drug delivery tube being configured to deliver a drug into the lumen;
- a first radiopaque marker on the housing;
- a second radiopaque marker on the housing and distanced from the first radiopaque marker;
- a drug delivery region including a proximal end and a distal end, the drug delivery region being established along the housing between the first radiopaque marker and the second radiopaque marker;
- and
- a drug delivery fenestration disposed on the proximal end and a drug delivery fenestration disposed on the distal end, the drug delivery fenestrations established in the housing within the drug delivery region configured to provide drug delivery from the lumen through the exterior surface of the housing, wherein the drug delivery region is configured to substantially straddle a fracture within the bone such that the drug delivery fenestration on the proximal end is positioned on one side of the fracture and the drug delivery fenestration on the distal end is positioned on another side of the fracture.
4 more elements
An intramedullary drug delivery device configured to be inserted within a bone canal of a bone, comprising:
- a housing extending along an axis between a first axial end and a second axial end opposite the first axial end, the housing comprising an opening in the first axial end, an exterior surface and an interior lumen;
- a drug delivery tube extending through the opening such that at least a portion of the drug delivery tube is positioned within the lumen, the drug delivery tube being configured to deliver a drug into the lumen;
- a first radiopaque marker on the housing;
- a second radiopaque marker on the housing and distanced from the first radiopaque marker;
- a drug delivery region including a proximal end and a distal end, the drug delivery region being, the drug delivery fenestrations established along the housing between the first radiopaque marker and the second radiopaque marker, the drug delivery region including a drug delivery fenestration disposed on the proximal end and a drug delivery fenestration disposed on the distal end, configured to provide drug delivery from the lumen through the exterior surface of the housing, wherein the drug delivery region is configured to substantially straddle a fracture within the bone such that the drug delivery fenestration on the proximal end is positioned on one side of the fracture and the drug delivery fenestration on the distal end is positioned on another side of the fracture;
- a first balloon adjacent to the drug delivery region;
- and
- a second balloon adjacent to the drug delivery region.
5 more elements
An intramedullary drug delivery device configured to be inserted within a bone canal of a bone, comprising:
- a housing extending along an axis between a first axial end and a second axial end opposite the first axial end, the housing comprising an opening in the first axial end, an exterior surface and an interior lumen;
- a drug delivery tube extending through the first opening such that at least a portion of the drug delivery tube is positioned within the lumen, the drug delivery tube being configured to deliver a therapeutic agent into the lumen;
- a drug delivery region including a proximal end and a distal end, the drug delivery region being configured to substantially straddle a fracture within the bone, the drug delivery region including a drug delivery fenestration disposed on the proximal end and a drug delivery fenestration disposed on the distal end, configured to provide drug delivery from the lumen through the exterior surface of the housing;
- a therapeutic agent deliverable to an area substantially near the fracture via the drug delivery region;
- and
- a balloon on the housing and movable between a deflated position and an inflated position.
3 more elements
A kit for treating a fracture within a bone, the kit comprising:
- an intramedullary drug delivery device configured to be inserted within the bone and comprising a housing extending along an axis between a first axial end and a second axial end opposite the first axial end, the housing comprising an opening in the first axial end, an exterior surface and an interior lumen, the drug delivery device comprising a drug delivery tube extending through the first opening such that at least a portion of the drug delivery tube is positioned within the lumen, the drug delivery tube being configured to deliver a therapeutic agent into the lumen, the drug delivery device further comprising a drug delivery region including a proximal end and a distal end, the drug delivery region being configured to substantially straddle the fracture, the drug delivery region including a drug delivery fenestration disposed on the proximal end and a drug delivery fenestration disposed on the distal end, configured to provide drug delivery from the lumen through the exterior surface of the housing, wherein the drug delivery fenestration on the proximal end is positioned on one side of the fracture and the drug delivery fenestration on the distal end is positioned on another side of the fracture;
- a therapeutic agent deliverable to an area within the bone substantially near the fracture via the drug delivery region;
- an intramedullary rod configured to be installed within the bone;
- and
- a balloon on the housing and movable between a deflated position and an inflated position.
2 more elements
Dependencies are inferred from the claim text.