Methods of preventing or treating anthrax using anti-anthrax antibodies

A method of preventing the development of inhalation anthrax in a human subject prior to exposure to B. anthracis spores, the method comprising administering intramuscularly a composition comprising an antibody which neutralizes B. anthracis toxin to the subject and further comprising administering at least one antibiotic to the subject to thereby preventing the development of inhalation anthrax in a human subject that prior to exposure to B. anthracis spores, wherein the antibody or binding molecule comprises the light chain variable region set forth as amino acid residues 1-107 in SEQ ID NO:2 and the heavy chain variable region amino acid sequence set forth as amino acid residues 1-119 in SEQ ID NO:1.

A method of treating inhalation anthrax in a human subject that has been exposed to B. anthracis spores, the method comprising administering intramuscularly a composition comprising an antibody which neutralizes B. anthracis toxin to the subject and further comprising administering at least one antibiotic to the subject to thereby treat inhalation anthrax in a human subject that has been exposed to B. anthracis spores, wherein the antibody comprises the light chain variable region set forth as amino acid residues 1-107 in SEQ ID NO:2 and the heavy chain variable region amino acid sequence set forth as amino acid residues 1-119 in SEQ ID NO:1.