Combinational chemotherapy treatment
AssigneeFox Chase Cancer Center
InventorYoshihiro Matsumoto
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Abstract
Disclosed is a composition comprising a therapeutically effective amount of (a) at least one compound from the group of 5-fluorouracil, 5-fluorodeoxyuridine, capecitabine or a prodrug of such compounds; and (b) 5-hydroxymethyl-2′-deoxyuridine, or a prodrug of such compound, as well as kits comprising such composition and methods of use thereof for treating neoplasia.
Claims13
A method of treating neoplasia in a patient in need thereof, said method comprising administering to said patient a therapeutically effective amount of:
- a) at least one compound selected from the group consisting of 5-Fluorouracil, 5-Fluorodeoxyuridine and capecitabine or other prodrug of 5-fluorouracil;
- and
- b) 5-hydroxymethyl-2′-deoxyuridine, or a prodrug thereof.
A composition comprising:
- a) at least one of the compounds selected from the group consisting of 5-Fluorouracil, 5-Fluorodeoxyuridine and capecitabine or other prodrug of 5-fluorouracil;
- and
- b) 5-hydroxymethyl-2′-deoxyuridine or a prodrug thereof and a pharmaceutically acceptable carrier.
A composition comprising heterodinucleoside phosphates consisting of 5-Fluorodeoxyuridine and 5-hydroxymethyl-2′-deoxyuridine.
Dependencies are inferred from the claim text.