Cancer therapy
AssigneeImmodulon Therapeutics Limited
InventorsCharles Akle, Satvinder Mudan, John Grange
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Abstract
The present invention relates to a method of preventing, treating or inhibiting the development of tumors or metastases in a subject and to an immunomodulator for use in such therapy, in combination with a chemotherapeutic agent. An aspect the present invention is a method of preventing, treating, reducing, inhibiting and/or controlling the formation or establishment of metastasis of a primary neoplasia, tumor or cancer at one or more sites distinct from a primary neoplasia, tumor or cancer, in a subject intended to undergo chemotherapy, wherein the method comprises administering to the subject, a therapeutically effective amount of an antimetabolite pyrimidine analogue and an immunomodulator.
Claims11
A method of preventing, treating, reducing, inhibiting and/or controlling the formation or establishment of metastasis of a primary neoplasia, tumour or cancer at one or more sites distinct from a primary neoplasia, tumour or cancer, in a subject intended to undergo chemotherapy, wherein said method comprises simultaneously, separately or sequentially administering to the subject, a therapeutically effective amount of (i) gemcitabine or a pharmaceutically acceptable salt, solvate, hydrate, stereoisomer, clathrate, or prodrug thereof;
- and (ii) an immunomodulator, comprising a whole cell Mycobacterium obuense;
- wherein the metastasis is associated with pancreatic cancer.
Dependencies are inferred from the claim text.