Devices and methods for facilitating controlled bone growth or repair
AssigneeDePuy Spine, Inc.
InventorDavid G. Malone
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AssigneeDePuy Spine, Inc.
InventorDavid G. Malone
Estimating the term…
Bone implantable devices and methodologies permit careful application of biologically active substances and management of bone growth processes. The device includes a body defining a carrier receiving area for locating adjacent bone. Carrier material is located in the carrier receiving area. Substance is delivered onto carrier material through a port. A pathway delivers substance from the carrier receiving area to the bone surface. The body may be in the form of a spinal fusion cage, facet fusion screw, artificial joint, bone fixation plate, interbody graft, IM nail, hip stem, or other bone-to-bone appliances or bone-to-device appliances. In use, carrier is installed in the carrier receiving area of the device. The device is then implanted adjacent a bone. The substance is applied to the carrier for subsequent delivery to the bone. By doping carrier material after device implantation, inadvertent contact of the substance with non-target bone is more easily eliminated.
An interbody spine fusion cage for promoting fusion between adjacent bone structures, comprising:
An apparatus to facilitate arthrodesis between bone structures while preventing bony overgrowth, comprising:
In a body having vertebral bodies defining a central canal, a spinal cord located in the central canal, neural elements branching out from said spinal cord through openings between the vertebral bodies, an arthrodesis facilitating therapeutic combination comprising:
An apparatus for insertion between adjacent vertebral bodies to facilitate arthrodesis between bone structures of the adjacent vertebral bodies while preventing bony overgrowth toward neural elements, comprising:
A cage to promote bony fusion of adjacent vertebral bodies comprising:
Dependencies are inferred from the claim text.
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Devices acting on, attached to, or simulating the effect of, vertebral processes, vertebral facets or ribs ; Tools for such devices: devices…
Internal fixation devices , including fasteners and spinal fixators, even if a part thereof projects from the skin: intramedullary devices, e.g.…
Internal fixation devices , including fasteners and spinal fixators, even if a part thereof projects from the skin: cortical plates , i.e. bone…
Pins or screws or threaded wires; nuts therefor: hollow, e.g. with socket or cannulated
Term ended 14 Dec 2020 (estimated)
1. Technical Field
This invention is directed generally to devices and methods for facilitating bone growth, and, in particular, to bone implantable devices and implantation methodologies that augment beneficial bone growth or repair while limiting bone growth in undesirable directions.
2. Background
FIG. 1 anatomically illustrates a bilateral posterior insertion of two inventive spine fusion cages to achieve fusion across the L5/S1 disc space.
FIG. 2 is an exploded perspective view of an embodiment of an inventive cage having preselected perforated and non-perforated zones on its outer surface.
FIG. 3 is a perspective view taken along line 3-3 of FIG. 2.
Before explaining the present invention in detail, it is important to understand that the invention is not limited in its application to the details of the construction illustrated and the steps described herein. The invention is capable of other embodiments and of being practiced or carried out in a variety of ways. It is to be understood that the phraseology and terminology employed herein is for the purpose of description and not of limitation.
As used herein the phrases “bone growth inducing agent(s),” “bone growth agent(s),” “bone growth accelerant”, “bone morphogenic protein(s),” and “BMP” refer synonymously to any substance useful in stimulating bone growth, whether a protein or not. Such substances are well known in the art.
As used herein the terms “carrier” and “carrier material” refer synonymously to any material capable of absorbing or otherwise holding or containing a bone growth inducing agent and which allows for the delivery of such agent to a target bone structure.