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US 8,617,135 B2Granted
System and method for closed-loop patient-adaptive hemodynamic management
AssigneeThe Regents of the University of California
InventorsJoseph B. Rinehart, Maxime Cannesson
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Abstract
A system and method for patient-adaptive hemodynamic management is described. One embodiment includes a system for hemodynamic management including transfusion, volume resuscitation with intravenous fluids, and medications, utilizing monitored hemodynamic parameters including the described dynamic predictors of fluid responsiveness, and including an intelligent algorithm capable of adaptation of the function of the device to specific patients.
Claims27
A computer-implemented method for facilitating the administration of an intravenous fluid to a patient in order to effect intravascular volume expansion, the method comprising:
- determining a first effect on a physiologic parameter of the patient associated with administration of a first fluid bolus to the patient wherein the first fluid bolus comprises a first quantity of a first intravenous fluid administered for the purpose of intravascular volume expansion;
- storing, using a processor, first information relating to the first effect in a first bolus log entry;
- determining a second effect on the physiologic parameter of the patient associated with administration of a second fluid bolus to the patient wherein the second fluid bolus comprises a second quantity of a second intravenous fluid administered for the purpose of intravascular volume expansion;
- storing, using a processor, second information relating to the second effect in a second bolus log entry;
- and
- generating, using the processor, a fluid administration signal useable to control the administration of the intravenous fluid wherein the fluid administration signal is based at least in part upon at least one of the first bolus log entry and the second bolus log entry.
3 more elements
A device, comprising:
- one or more processors;
- and
- a memory operatively coupled to the one or more processors, the memory storing program code which, when executed by the one or more processors, determines a first effect on a physiologic parameter of the patient associated with administration of a first fluid bolus to the patient wherein the first fluid bolus comprises a first quantity of a first intravenous fluid administered for the purpose of intravascular volume expansion, stores first information relating to the first effect in a first bolus log entry within device storage, determines a second effect on the physiologic parameter of the patient associated with administration of a second fluid bolus to the patient wherein the second fluid bolus comprises a second quantity of a second intravenous fluid administered for the purpose of intravascular volume expansion, stores second information relating to the second effect in a second bolus log entry within the device storage, and generates a fluid administration signal useable to control the administration of an intravenous fluid wherein the fluid administration signal is based upon at least one of the first bolus log entry and the second bolus log entry.
An infusion system, comprising:
- a pump apparatus configured to control delivery of an intravenous fluid to a patient to effect intravascular volume expansion;
- and
- a controller that determines a first effect on a physiologic parameter of the patient associated with administration of a first fluid bolus to the patient wherein the first fluid bolus comprises a first quantity of a first intravenous fluid administered for the purpose of intravascular volume expansion, stores first information relating to the first effect in a first bolus log entry within device storage, determines a second effect on the physiologic parameter of the patient associated with administration of a second fluid bolus to the patient wherein the second fluid bolus comprises a second quantity of a second intravenous fluid administered for the purpose of intravascular volume expansion, stores second information relating to the second effect in a second bolus log entry within the device storage, and provides a fluid administration signal to the pump apparatus based upon at least one of the first bolus log entry and the second bolus log entry wherein the fluid administration signal is useable to control the administration of the intravenous fluid.
Dependencies are inferred from the claim text.