Device for delivery of a foamable composition

A kit for delivery of a foamable composition comprising:

• a pressurized canister comprising a foamable composition comprising an active ingredient;
• a hollow body having distal and proximal ends and a plurality of apertures comprising at least first and second apertures provided through a side wall of said hollow body, the proximal end in fluid communication with the reservoir via an actuator, said hollow body being shaped and adapted for insertion within a body cavity;
• an actuator operatively connected to the composition reservoir for effecting release of the foamable composition from said composition reservoir into a body cavity through said hollow body;
• and
• a port for providing fluid communication between said hollow body and said actuator;
• wherein the plurality of apertures of the hollow body are located at distances from said proximal end that are within the range from about 90% to about 25% of the length of said hollow body and said hollow body lacks an aperture at its distal end;
• wherein said first aperture is located closer to the distal end, and said second aperture is located closer to the proximal end;
• wherein the aperture size of said first aperture is larger than the aperture size of said second aperture;
• and
• wherein said hollow body has a length and internal diameter selected for optimal delivery of the foamable composition to the body cavity.

A device comprising:

• a pressurized canister containing a foamable composition;
• a catheter having a first and second catheter end;
• wherein the catheter is sufficiently flexible to conform to the contours of a body cavity into which it is inserted and is suitable for delivering the foamable composition into a deep body cavity and deliver the foam to a target area within the deep body cavity;
• a connector that connects the canister to the catheter at the first catheter end which, when connected, provides a first pressure sensitive seal so that foam released from the canister passes into and through the catheter without escaping through the first pressure-sensitive seal;
• the second catheter end suitable for discharging foam or for receiving a foam applicator;
• wherein the foam applicator is adapted to discharge foam into a body cavity and when connected to the second catheter end provides a second pressure sensitive seal so that foam does not escape from the second pressure-sensitive seal;
• and
• wherein the pressurized canister comprises an actuator including a valve and port and the connector connects with the canister at the port to provide the first pressure sensitive seal.

A device for delivery of a foamable composition to a body cavity, the device comprising:

• a hollow body having distal and proximal ends, an inner diameter, and a plurality of apertures comprising at least first and second apertures provided through a side wall of said hollow body, the proximal end adapted to be in fluid communication with a reservoir via an actuator for receiving a foamable composition, said hollow body being shaped and adapted for insertion within a body cavity;
• and
• an actuator including a valve and port operatively connected to the hollow body for effecting release of a foamable composition from said hollow body;
• wherein the plurality of apertures of the hollow body are located at distances from said proximal end that are within the range from about 90% to about 25% of the length of said hollow body and said hollow body lacks an aperture at its distal end;
• wherein said first aperture is located closer to the distal, and said second aperture is located closer to the proximal end;
• wherein the aperture size of said first aperture is larger than the aperture size of said second aperture;
• and
• wherein the location and relative size of said first and second apertures are selected to provide delivery of the foam in a preselected proportion from each aperture so as to provide the maximal coverage of a body coverage with the minimal amount of foamable composition.